Comparative Effectiveness Trial for Diabetic Macular Edema
نویسندگان
چکیده
منابع مشابه
Remote Ischemic Preconditioning and Diabetic Macular Edema
Objective: Remote Ischemic Preconditioning (RIPC) as the transient ischemia and reperfusion of the arm is a promising method for protecting different tissue from future ischemia. These effects might be mediated through vascular and endothelial growth factor (VEGF) pathway. We investigated the influence of RIPC on diabetic macular edema (DME) as a chronic ischemic condition in patients who were ...
متن کاملAflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema: Two-Year Results from a Comparative Effectiveness Randomized Clinical Trial.
PURPOSE To provide 2-year results comparing anti-vascular endothelial growth factor (VEGF) agents for center-involved diabetic macular edema (DME) using a standardized follow-up and retreatment regimen. DESIGN Randomized clinical trial. PARTICIPANTS Six hundred sixty participants with visual acuity (VA) impairment from DME. METHODS Randomization to 2.0-mg aflibercept, 1.25-mg repackaged (...
متن کاملDiabetic Macular Edema
Introduction Over the last one decade the management of diabetic macular edema has undergone a paradigm change. This is attributed to the newer diagnostic tests and pharmacological agents. There are enough good randomized controlled trials to prove the efficacy of these drugs. However, in clinical practice, there are many situations where the application of the findings of these clinical trials...
متن کاملRefractory Diabetic Macular Edema
Diabetic macular edema (DME) is arguably one of the most important challenges in ophthalmology. Macular edema refractory to laser photocoagulation remains the most prevalent cause of untreatable vision loss in diabetes and is responsible for visual disability in millions of people worldwide. The lack of an effective therapeutic solution accounts for the range of interventions proposed. These in...
متن کاملDiabetic Macular Edema
UNLABELLED Diabetic macular edema (DME), one the most prevalent causes of visual loss in industrialized countries, may be diagnosed at any stage of diabetic retinopathy. The diagnosis, treatment, and follow up of DME have become straightforward with recent developments in fundus imaging, such as optical coherence tomography. Laser photocoagulation, intravitreal injections, and pars plana vitrec...
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ژورنال
عنوان ژورنال: JAMA Ophthalmology
سال: 2015
ISSN: 2168-6165
DOI: 10.1001/jamaophthalmol.2015.1880